Tag Archives: Infectious disease
doctor uses tablet with patient

‘Urinary Tract Infection’ and the Microbiome

The current paradigm for managing uncomplicated “urinary tract infection” (“UTI”) is deeply flawed. “UTI” is ambiguously defined, and coupled with a belief that “bacteria are not normal inhabitants of the urinary tract,”1 the diagnosis often leads to unnecessary, harmful antibiotic treatment. Although bacteriuria identified by standard clinical cultures (which we will call standard bacteriuria) is central […]

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Stubborn Creatures: Dormant Staphylococcus aureus

A healthy 70-year-old woman was admitted with a 3-day history of a pus-emitting wound on her left shin, in the absence of trauma. She was afebrile, and examination was normal excepting a warm, erythematous and tender area over her left distal tibia with a central swollen area discharging pus. Hemoglobin was 11.7 g/dL, white blood […]

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Herpes Zoster Ophthalmicus: A Review for the Internist

Herpes zoster ophthalmicus occurs due to reactivation of the varicella zoster virus in the ophthalmic branch of the fifth cranial nerve. This disease primarily affects the elderly as well as the immunocompromised and can result in a wide range of ophthalmic morbidity. Systemic antiviral therapy is the mainstay of treatment; however, consultation with an ophthalmologist […]

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Abdominal Tuberculosis Presenting as a Malignant Masquerader

  A previously healthy, immunocompetent, US-born, 48-year-old black woman presented with 6 months of subjective fevers, night sweats, and intermittent abdominal pain. Initial computed tomography scan (Figure 1) revealed a pancreatic versus peripancreatic mass and multiple liver lesions concerning for metastatic pancreatic cancer; percutaneous fine-needle aspiration (FNA) of the liver lesions revealed inflammatory changes and no […]

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close up of a mosquito on skin

Re-Emergence of Zika Virus: A Review on Pathogenesis, Clinical Manifestations, Diagnosis, Treatment, and Prevention

  Zika virus (ZKV) is an arbovirus of the Flaviviridae family, which includes West Nile, dengue fever, yellow fever, and Japanese encephalitis virus. It is transmitted by the Aedes genus of mosquitoes. Before 2015, ZKV outbreaks occurred in areas of Africa, the Pacific Islands, and Southeast Asia. The current large outbreak, which began in Brazil, has also […]

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