Tag Archives: Infectious disease

Koplik’s Spots and Measles

To the Editor: Measles, one of the most transmissible diseases, is most contagious before rash manifestation. Search for the pathognomonic Koplik’s spots could be critical for the early diagnosis in this prodromal period. Case Description A 47-year-old man had high-grade fever with a peak temperature of 39.7°C, photophobia, rhinitis, and dry cough. On the fifth […]

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Straight Talk About Chronic Lyme Disease

Four years ago, we noted an example of irresponsible reporting on Lyme disease by an investigative television news team.1 Consequently, when we learned that this same group was airing a new 5-part series entitled, “The Lyme Wars: Investigating a Public Health Crisis,” we were most interested to see if they had done a better job this […]

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One Thing after Another: Ecthyma Gangrenosum

Chronic high-dosage steroid therapy can pose a significant risk factor for infection due to its immunosuppressive effect. A 70-year-old African American man presented with acute bilateral painless vision loss. An investigative work-up produced a positive antinuclear antibody titer of 1:1280 with a speckled pattern, a positive test for anti-Ro/anti-Sjögren’s-syndrome-related antigen A antibody, and an erythrocyte […]

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Platelet Count of Zero: A Curious Case of Thrombocytopenia

To read this article in its entirety please visit our website. -Patrick Twohig, MD, MPH, Jaclyn Rivington, MD This article originally appeared in the November 2017 issue of The American Journal of Medicine.

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Post-Polio-Like Syndrome

  Post-polio syndrome is a motor neuron disease that occurs in 15%-80% of patients with a history of polio.1 The diagnostic criteria for post-polio syndrome include a confirmed history of polio, partial or complete neurologic and functional recovery after acute polio, a period of more than 15 years with neurologic and functional stability, new symptoms that […]

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