Tag Archives: carcinoma
The trigeminocardiac reflex pathway diagram. 1) Trigeminal ganglion via sensory fibers of trigeminal nerve. 2) Sensory nucleus of trigeminal nerve. 3) Internuncial fibers. 4) Motor nucleus of the vagus nerve. 5) Efferent vagal nerve to the heart and stomach.

Trigeminocardiac Reflex as the Presentation of Maxillary Sinus Adenocarcinoma

A 54-year-old man with history of tobacco use presented to the Emergency Department with a few-hour history of dizziness and 2-month history of intermittent right jaw pain. His blood pressure was 68/48 mm Hg, heart rate was 55 beats per minute, and oxygen saturation was 85% on room air. Physical examination was notable for a […]

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Screening for Hepatocellular Carcinoma in Patients with Cirrhosis: A Need to Increase Awareness

Hepatocellular carcinoma is the most common primary liver cancer, occurring largely in patients with cirrhosis. The incidence of hepatocellular carcinoma is rising in the US, as is its mortality, making hepatocellular carcinoma one of the leading causes of cancer-related deaths in the country.1 Despite the fact that early detection improves survival in patients with hepatocellular carcinoma, […]

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Hepatocellular Carcinoma Screening Associated with Early Tumor Detection and Improved Survival Among Patients with Cirrhosis in the US

Professional societies recommend hepatocellular carcinoma screening in patients with cirrhosis, but high-quality data evaluating its effectiveness to improve early tumor detection and survival in “real world” clinical practice are needed. We aim to characterize the association between hepatocellular carcinoma screening and early tumor detection, curative treatment, and overall survival among patients with cirrhosis. Methods We […]

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Portable chest x-ray on presentation (A) and follow-up computed tomography of the chest without contrast (B).

Not Just Skin Deep: Distant Metastases from Cutaneous Squamous Cell Carcinoma

  Cutaneous squamous cell carcinoma is the second most common cancer in the United States and has 5-year recurrence and metastasis rates of 8% and 5%, respectively.1, 2 However, not all cutaneous squamous cell carcinomas are alike, and the size and location of the primary lesion confers a widely variable risk for recurrence and metastasis. Case Summary […]

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Independent of Cirrhosis, Hepatocellular Carcinoma Risk Is Increased with Diabetes and Metabolic Syndrome

Hepatocellular carcinoma is the most common primary liver malignancy, commonly a sequelae of hepatitis C infection, but can complicate cirrhosis of any cause. Whether metabolic syndrome and its components, type II diabetes, hypertension, and hyperlipidemia increase the risk of hepatocellular carcinoma independent of cirrhosis is unknown. Methods A retrospective cohort study was conducted using the MarketScan insurance […]

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(A) Left temporal cutaneous lesion prior to immunotherapy. (B) Left temporal cutaneous lesion after 7 cycles of immunotherapy.

Immunotherapy in Squamous Cell Skin Carcinoma: A Game Changer?

  A 74-year-old white male was diagnosed with squamous cell carcinoma in 2013. Six months after Mohs surgery, he underwent a left superficial parotidectomy, left neck dissection, and excision of the left postauricular lymph node after confirmation of lymphatic spread. Pathology from the left parietal scalp lesion revealed multifocal invasive squamous cell carcinoma. Extranodal tumor […]

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