American Journal of Medicine, internal medicine, medicine, health, healthy lifestyles, cancer, heart disease, drugs

Geographic Variability in Liver Disease-Related Mortality Rates in the United States

Liver disease is an important cause of morbidity and mortality in the United States. Geographic variations in the burden of chronic liver disease may have significant impact on public health policies but have not been explored at the national level. The objective of this study is to examine interstate variability in liver disease mortality in […]

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Importance of Genetic Testing in the Diagnosis of Transthyretin Cardiac Amyloidosis

To the Editor: Systemic amyloidosis results from extracellular deposition of fibrillar material derived from aggregation of precursor proteins into insoluble beta-pleated sheets. The most frequently recognized types are due to prolonged inflammation, deposition of immunoglobulin light chains, and accumulation of transthyretin, a tetrameric protein synthesized in the liver. Transthyretin amyloidosis can occur owing to wild-type […]

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Vena Cava Compression Syndrome in Obesity is Reversed by Bariatric Surgery

To the Editor: Obesity is a major public health problem, with a prevalence of 10% to 20% in Western Europe.1 It is a risk factor for arterial hypertension, atherosclerosis, and heart failure.2 In times of rising prevalence in obesity, bariatric surgery offers an effective way to achieve weight loss.2 The indication for bariatric surgery is provided by interdisciplinary […]

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Medical Axioms: The Pithy Little Sayings That Reflect Deeper Knowledge

  I love axioms. Perhaps it is the result of hearing them from one of my earliest mentors in medical school. Or perhaps it is the result of advice given me by my journalist/English teacher mother who told me that everything you write can be improved by condensation. Whatever the underlying reason, I continue to […]

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Thoracoabdominal Aneurysm in a Professional Body Builder

To the Editor: A 33-year-old otherwise healthy man presented with worsening epigastric and flank pain for 3 weeks. He denied having vomiting, diarrhea, fever, urinary symptoms, or history of kidney stones. His vital signs were significant for a blood pressure of 140/72 mm Hg and pulse rate of 94 beats/min. Acute coronary syndrome was excluded by electrocardiography. A […]

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Hypertriglyceridemia-Induced Acute Pancreatitis with Normal Pancreatic Enzymes

To the Editor: The diagnosis of acute pancreatitis requires 2 of the following 3 features: 1) abdominal pain consistent with acute pancreatitis; 2) serum lipase activity (or amylase activity) at least 3 times greater than the upper limit of normal; and 3) characteristic imaging findings of acute pancreatitis.1 Although normal serum amylase levels have been reported […]

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Skin and Nasal Involvement: Look for Sarcoidosis!

  Sarcoidosis is a systemic, noncaseating, granulomatous disease affecting young adults between the ages of 25 and 40 years, most often of Black origin (35.5/100,000 vs 10.9 in the White population). Although the lower respiratory tract is affected in 90% of cases, ear, nose, and throat locations are very uncommon, with a prevalence varying between […]

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doctor uses tablet with patient

Diabetes Mellitus and Cardiogenic Shock Complicating Acute Myocardial Infarction

Diabetes mellitus (diabetes) increases the risk of acute myocardial infarction, which can result in cardiogenic shock. Data on the relation of diabetes and the occurrence and prognosis of cardiogenic shock postacute myocardial infarction are scant. Methods Among the National Inpatient Sample patients aged ≥18 years and hospitalized for acute myocardial infarction during the 2012-2014 period, […]

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young female doctor examines x-ray

From Mechanical to Chemical: A Case of Diabetes Insipidus Induced by Concussive Brain Injury

Diabetes insipidus is a rare disorder of water-electrolyte balance characterized by either absolute (central) or functional (nephrogenic) deficiency of vasopressin or antidiuretic hormone.1 Central diabetes insipidus is a recognized complication of traumatic brain injury; however, those patients are much sicker and have other symptoms from the trauma as well.2 We present a case of complete central diabetes […]

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Polymyalgia Rheumatica with Normal Inflammatory Markers

A 70-year-old man presented with pain in his shoulders, low back, and thighs for 1 year. He had difficulties when changing clothes, taking a bath, and getting out of bed because all these body movements aggravated the pain. He also experienced morning stiffness for 1 hour. Although his weight decreased by 5 kg because of loss […]

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